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FETAL DIAGNOSES & TREATMENT
A number of
potentially fatal birth defects can be detected and treated before a
child’s birth because
of the availability of expertise in all types of fetal
abnormalities, world-class imaging
techniques
and diagnostic testing available
at Texas Children's
Fetal Center.
While most birth
defects are best managed with medical therapy during pregnancy or
with surgery immediately after birth, an increasing number of
anatomic abnormalities can be corrected before birth to reduce some
of the life-threatening or devastating consequences of the defect.
Our experienced team of experts
evaluate and treat the following conditions:
| Abdominal Wall
Defects |
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Gastroschisis |
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Omphalocele |
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| Amniotic Band
Syndrome |
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| CNS Lesions |
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Hydrocephalus |
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Hydrancephaly |
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Anencephaly |
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Holoprosencephaly |
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Encephalocele |
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| Congenital Airway
Obstruction (CHAOS) |
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Congenital
Diaphragmatic Hernia |
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Congenital Heart Disease |
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| Craniofacial
Anomalies |
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Cleft Lip |
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Cleft Palate |
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| Duodenal and
Intestinal Atresia |
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| Esophageal Atresia
with Tracheoesophageal Fistula |
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| Fetal
Cardiac Arrhythmias |
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| Fetal Chylothorax
or Hydrothorax |
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Giant Neck Masses |
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| Lung Lesions |
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Congenital Cystic Adenomatoid Malformation
(CCAM) |
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Hybrid Lesions |
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Pleuro Pulmonary
Blastoma |
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Pulmonary
Sequestration |
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| Maternal Immune
Disorders Affecting the Fetus |
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Congenital Heart
Block |
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Platelet
Alloimmunization |
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Red Cell
Alloimmunization |
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| Myelomeningocele (Spina
Bifida) |
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| Non-immune Hydrops |
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| Small Bowel
Obstruction |
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Sacrococcygeal Teratoma |
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| Skeletal Dysplasia |
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| Twin Abnormalities |
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Twin-Twin
Transfusion Syndrome (TTTS) |
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Discordant
Intrauterine Growth Restriction (IUGR) |
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Discordant
Structural Anomalies |
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TRAP Sequence (acardiac
twin) |
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Urinary Tract Obstruction |
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Bladder Outlet
Obstruction |
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Hydronephrosis |
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During the birthing process, blood cells from the unborn child can
escape into the mother's bloodstream. These cells are recognized as
foreign if they are a different blood type from the mother and a
natural rejection process will ensue with the formation of
antibodies. The process is known as red cell alloimmunization. In
severe cases, the maternal antibodies can cross the placenta and
cause fetal anemia and hydrops (heart failure) Platelet
alloimmunization: Differences in proteins on platelets can also
cause the formation of maternal antibodies. In these cases
antibodies can cross the palcenta and cause a low platelet count in
the fetus. This can lead to bleeding into the fetal brain.
Learn
more
Congenital
diaphragmatic hernia (CDH) occurs when the diaphragm does not fully
form, allowing organs like the stomach, spleen, liver, and
intestines to enter the chest cavity and preventing lung growth. The
defect can occur on the right or left side or both, but left side
CDH is most common. It is suggested that the presence of abdominal
organs in the chest cause the devastating effects in the developing
lungs. One in every 2,500 babies is afflicted by CDH, which can
cause minor lasting health problems such as feeding aversions,
asthma, scoliosis and short-term oxygen dependency – or major
ongoing health problems, including ventilator dependency, brain
damage, hearing problems and death. Learn
more
Lungs are
normally divided into sections called lobes, with three on the right
and two on the left. A congenital cystic adenomatoid malformation (CCAM)
is a cystic mass of abnormal, dysfunctional lobe that appears as a
fluid-filled sac called a cyst. Most CCAMs either disappear or are
too small to cause problems. Typically, they are benign, but in rare
cases may become cancerous or infected and cause pneumonia.
Giant fetal neck masses, such as cervical teratoma and lymphatic
malformation, can grow to such large proportions that the fetal
airway becomes distorted and obstructed. In addition to obstructing
the airway, these masses can compress the esophagus, resulting in
polyhydramnios, uterine irritability and preterm labor.
Fetal
sacrococcygeal teratoma (SCT) is a nonmalignant tumor located at the
base of the tailbone. Occurring in one in every 35,000 to 40,000
live births, it is the most common tumor in newborns. These tumors
can grow to large proportions and contain large blood vessels that
rob the developing fetus of blood. SCTs are cancerous 10 percent of
the time.
Spina bifida is a birth defect in which the
bones of the spine (vertebrae) do not form properly around the
spinal cord. This can occur anywhere along the spine. Spina bifida
is the most common of a group of birth defects called neural tube
defects. The role of fetal surgery in managing fetuses with this
condition is the subject of a national trial called
Management of Myelomeningocele Study
(MOMS).
This
condition occurs only in those identical twins that are
monochorionic, diamniotic The single placenta contains blood vessel
connections between the twins and in 15 percent to 20 percent of monochorionic, diamniotic twins, the blood flow through these blood
vessel connections becomes unbalanced. In TTTS, the smaller twin
(often called the donor twin) does not get enough blood while the
larger twin (often called the recipient twin) becomes overloaded
with too much blood.
Learn more.
Abnormalities of
the genitals and urinary tract are among the most common birth
defects, affecting as many as one in 10 babies. Male fetuses can
have an obstruction to the flow of urine out the bladder, causing
urine to back up and damage the kidneys. Consequently, the amniotic
fluid becomes filled with disproportionate amounts of urine, and the
low amniotic fluid levels cause inadequate lung development. In the
event of renal and pulmonary failure, this fetal condition can be
life threatening.

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